What is Telmisartan?
Telmisartan is an AT1 receptor blocker with the longest half-life of all sartans (about 24 hours). This means a particularly uniform 24-hour blood pressure protection, even in the critical early hours.
Known brand names are Kinzalmono® and Micardis®. Telmisartan is also available in combination with hydrochlorothiazide (Micardis® Plus). It also has a mild PPAR-gamma activation, which can have a positive effect on metabolism.
Active Ingredients & Mechanism of Action
Active ingredient: Telmisartan
Telmisartan blocks the AT1 receptor particularly long-lasting:
Active mechanism:
- High-selective and long-lasting AT1 blockade
- Longest half-life of all Sartane (about 24 hours)
- Lipophile – high tissue penetration
Additional properties:
- Mild PPAR-gamma activation (substance-promoting)
- Can easily improve insulin resistance
- Cheap effects on lipid metabolism
Clinical meaning: In the ONTARGET study, Telmisartan was equivalent to the ACE inhibitor Ramipril in high-risk patients.
Who is it suitable for?
Telmisartan is suitable for:
- Adults with high blood pressure
- cardiovascular prevention in high risk patients
- Patients who need a reliable 24-hour action
Especially recommended at:
- Early blood pressure (low blood pressure)
- Metabolic syndrome
- Patients who do not use Ramipril
Not suitable:
- Pregnancy and breastfeeding
- Gallenwegsobstruction
- Heavy liver failure
Available Dosages
High blood pressure:
- Start dose: 40 mg once a day
- usual dose: 40-80 mg once a day
- Maximum dose: 80 mg daily
Cardiovascular prevention:
- 80 mg once a day
Available starches:
- 20 mg, 40 mg, 80 mg tablets
Combination:
- Telmisartan + Hydrochlorothiazid (Micardis® Plus)
How to Take
Intake:
- Once a day, if possible in the morning
- Independent meals
- Take with water
- Do not share or chew tablet
**
- Regular blood pressure controls
- Laboratory controls (animal, potassium)
- Do not drop abruptly
Contraindications
**Telmisartan must not be taken at:* *
- hypersensitivity to Telmisartan
- Pregnancy and breastfeeding
- Gallenwegsobstruction
- Heavy liver failure
- At the same time with aliens in diabetes
Preview at:
- Kidney failure
- Kidney artery stenosis
- Hyperkaliemia
- Primary hyperaldosteronism
pregnant: Strikt contraindicates throughout pregnancy.
Possible Side Effects
** Occasionally (0,1-1%):* *
- Squeeze
- urinary tract infections
- infections of the upper respiratory tract
- Back pain
- Gastrointestinal complaints
Selten:
- Hyperkaliemia
- Kidney function reduction
- Angioedema
- Liver malfunction
Good tolerated: Telmisartan has shown in studies a compatibility that is hardly above placebo levels. It is one of the best tolerated blood pressure medications.
Interactions
Contracted:
- Aliskiren in diabetes or kidney failure
Preview at:
- Potassium-saving diuretics → Hyperkaliemia
- NSAR → reduced effect
- Lithium → raised mirrors
- Digoxin → mirror increase possible
Fabric change: Telmisartan is not degraded via CYP enzymes, so little interactions about this path.
Frequently Asked Questions
Similar Medications
Is Telmisartan right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.