What is Avanafil?
Avanafil is the active ingredient of the Spedra brand product and has also been available as a generic product since the patent procedure. It is the youngest and fastest PDE-5 inhibitors on the market.
The generics contain the same active ingredient and offer the same fast effect as the original, but at a cheaper price.
The action can already take place after 15 minutes – significantly faster than in Sildenafil (30-60 min) or Tadalafil (30 min).
Active Ingredients & Mechanism of Action
Active ingredient: Avanafil
Avanafil inhibits the enzyme phosphodiesterase-5 (PDE-5) in the swelling body. This keeps the messenger substance cGMP active longer, the blood vessels relax and more blood can flow into the penis.
Advantages of Avanafil:
- Fastest absorption of all PDE-5 inhibitors
- High selectivity for PDE-5
- Possible fewer side effects
Who is it suitable for?
Avanafil generics are suitable for men who:
- Need quick action
- Want to save costs (more favourable than Spedra)
- Miscellaneous PDE-5 inhibitors
Available Dosages
- 50 mg
- 100 mg
As with Spedra: start with 100 mg, adjustment depending on the effect.
How to Take
15-30 minutes before intercourse, with or without food.
Contraindications
Identical with Spedra: No combination with nitrates, contraindicated in severe heart disease.
Possible Side Effects
Headache, flush, clogged nose, dizziness – as with all PDE-5-inhibitors.
Frequently Asked Questions
Similar Medications
Is Avanafil right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.




