What is Seebri Breezhale?
Seebri Breezhaler is a long-acting anticholinergic agent (LAMA) with the active ingredient glycopyrronium bromide. It is used for bronchial-enhancing continuous therapy at COPD and has to be inhaled only once a day.
The Breezhaler is a capsule inhaler: A capsule is placed, pierced and the powder is inhaled. Surrene of the capsule confirms the correct inhalation.
Glycopyrronium is also part of the triple inhaler Trimbow. Seebri is manufactured by Novartis.
Active Ingredients & Mechanism of Action
Active ingredient: Glycopyrroniumbromid
Glycopyrronium blocks muscular receptors:
Active mechanism:
- Inhibits M3-muscarin receptors in the bronchi
- Blocks the bronchoconstrictor effect of acetylcholine
- Extends the airways
- Reduced mucus secretion
Time:
- Fast action: within 5 minutes
- duration of action: 24 hours
- Maximum effect: 1-4 hours
Advantage: Faster action than tiotropium with comparable 24-hour action.
Who is it suitable for?
Seebri Breezhaler is suitable for:
- COPD continuous therapy in adults
- As a bronchodilatator monotherapy
- In combination with LABA and/or ICS
Advantages:
- Fast action
- Once a day
- Acoustic feedback (Kapsel surrt)
Not suitable:
- For asthma as monotherapy
- As an emergency medication
- For children and young people
Available Dosages
Seebri Breezhaler:
- 44 μg glycopyrronium per capsule
- Inhale 1 capsule once a day
**
- Don't swallow capsules!
- Always inhale at the same time of the day
How to Take
Breezhaler (capsule inhaler): 1. Protective cap remove Two. Open mouthpiece 3. Insert capsule into the chamber 4. Close mouthpiece Five. Press side keys simultaneously (capsule is pierced) 6. Breathe deep (not in the inhaler) 7. Close the mouthpiece 8. Strong and deep breathing 9. Capsule must surre – if not, breathe again 10. Keep breath 11. Check capsule – inhale again for residual powder
Important:
- Take capsules from the blister just before use
- Do not swallow capsules
Contraindications
Do not apply at:
- hypersensitivity to glycopyrronium or lactose
Preview at:
- Engangle glaucoma
- Prostate hyperplasia
- Heavy kidney failure
- Severe heart disease
pregnant: Limited data. Only with clear indication.
Style time: Not recommended.
Possible Side Effects
Acid (1-10%):
- Mouth dryness
- Nasopharyngitis
- Sleep disorders
- urinary tract infections
Occasionally:
- Squeeze
- Harnverhalt
- Gastrointestinal complaints
- Skin rash
Selten:
- Engangle glaucoma
- Paradox bronchospasmus
** Regular drinking helps against dry mouth.
Interactions
Preview at:
- Other anticholinergics (additive action)
- QT-extending medications
Ingenious combination:
- With LABA (e.g. Indacaterol)
- With ICS as needed
Frequently Asked Questions
Similar Medications
Is Seebri Breezhale right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.