What is Aarane?
Aarane is a combination inhaler containing cromoglic acid (a mast cell stabilizer) and reproterol (a short-acting beta-2-sympathomimetic). It is used to prevent bronchiale asthma.
Cromoglic acid stabilizes mast cells and prevents the release of inflammatory mediators, while reproterol expands the bronchi. The combination thus offers a double effect.
Aarane is more rarely prescribed today, since inhalative corticoids are more effective. However, it can be used in light allergic asthma or as an alternative in corticoid intolerance.
Active Ingredients & Mechanism of Action
Active ingredient: Cromoglicinsäure, Reproterolhydrochlorid
Aarane combines two mechanisms of action:
Cromoglicic acid (mass cell stabiliser):
- Stabilizes the membrane of mast cells
- Prevents release of histamine and leukotriene
- Preventing allergic reactions
- No direct bronchial enhancement effect
Reproterol (SABA):
- Activated beta-2-adrenoceptors
- Fast bronchodilation
- duration of action: 4-6 hours
- Additional light antiallergic effect
Combined action: Preventive (Cromoglicic Acid) plus symptomatic (Reproterol) in an inhaler.
Who is it suitable for?
Aarane is suitable for:
- Light allergic asthma
- Load-induced asthma (prophylactic)
- Allergeninduced asthma
- Children with light asthma
Restrictions:
- Less effective than inhalative corticoids
- Preventive effect of cromoglic acid
- No effect in acute asthma attack (for cromoglic acid)
Not suitable:
- For medium to heavy asthma
- As sole acute therapy
Available Dosages
Aarane dosing aerosol:
- 1 mg cromoglic acid + 0.5 mg reproterol per stroke
- 2 strokes 4x daily
- Before allergen exposure: 2 strokes 10-15 min. before
- Before sport: 2 strokes 10-15 min. before
How to Take
Dosieraerosol: 1. Remove protective cap, shake Two. Deep exhalation 3. Close the mouthpiece 4. Breathe slowly, spray Five. Keep breath 10 seconds 6. Second stroke after 30 seconds
Important:
- Regularly apply (preventive effect!)
- In addition to known allergen exposure
- Before sports to prophylaxis
Contraindications
Do not apply at:
- hypersensitivity to the active ingredients
Preview at:
- Severe heart disease
- thyroid hyperfunction
- phenochromocytoma
pregnant: Limited data. Only with clear indication.
Style time: Application after Benefit Risk weighing.
Possible Side Effects
**
- Husten after inhalation
- Rache irritation
Occasionally:
- Tremor (by Reproterol)
- Heart palp
- Headaches
- Taste disorders
Selten:
- Paradox bronchospasmus
- Allergic reactions
Interactions
Reactions:
- Betablockers – can eliminate reproterol action
- MAO inhibitors – enhanced heart action
No relevant interaction with:
- Inhalative corticoids
- Antihistamines
Frequently Asked Questions
Similar Medications
Is Aarane right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.